課程大綱

課程資訊

課程名稱	書報討論（二） SEMINAR (B.S.)(2)
開課學期	97-2
授課對象	生命科學系
授課教師	李心予
課號	LS4002
課程識別碼	B01 40020
班次	04
學分	1
全/半年	半年
必/選修	必帶
上課時間	星期二7,8(14:20~16:20)
上課地點	生科3C
備註	與陳香君、鄭秋萍合開限學號末二位被４整除且限本系所學生(含輔系、雙修生) 總人數上限：25人
Ceiba 課程網頁	http://ceiba.ntu.edu.tw/972_Seminar
課程簡介影片
核心能力關聯	核心能力與課程規劃關聯圖
課程大綱
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課程概述	本課程以學生輪流上台發表學術演講為主軸,其他同學則需聽講並參予討論。每人每學期以演講一次為原則,並需擔任一次主持人,負責介紹當次演講者背景、演講主題、主持討論和掌控時間等工作。
課程目標	培養學生檢索、選擇、閱讀期刊論文與演講發表之能力, 同時參予其他同學之演講,藉以獲得學術研究之啟蒙。
課程要求
預期每週課後學習時數
Office Hours
指定閱讀
參考書目
評量方式 (僅供參考)

課程進度

週次	日期	單元主題
第1週	2/17	class organization
第2週	2/24	break
第3週	3/3	楊軒-Brosh R., Shalgi R., Liran A., Landan G., Korotayev K., Nguyen G.H., Enerly E., Johnsen H., Buganim Y., Solomon H., Goldstein I., Madar S., Goldfinger N., Børresen-Dale A.L., Ginsberg D., Harris C.C., Pilpel Y., Oren M., and Rotter V. (2008). p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation. Molecular Systems Biology 4:229. 張景賀-Barbero F., Thomas J.A., Bonelli S., Balletto E., and Sch"onrogge K. (2009). Queen Ants Make Distinctive Sounds That Are Mimicked by a Butterfly Social Parasite. Science 323: 782 – 785.
第4週	3/10	林育生-Kawahara T.L.A., Michishita E., Adler A.S., Damian M., Berber E., Lin M., McCord R.A., Ongaigui K.C.L., Boxer L.D., Chang H.Y., and Chua K.F. (2009). SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-kB-Dependent Gene Expression and Organismal Life Span. Cell 136: 62–74. 李崢嶸-Blackburn S.D., Shin H., Haining W.N., Zou T., Workman C.J., Polley A., Betts M.R., Freeman G.J., Vignali D.A., Wherry E.J. (2009). Coregulation of CD8-positive T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat. Immunol. 10(1): 29-37.
第5週	3/17	李岱威-Brozzi F., Arcuri C., Giambanco I., and Donato R. (2009). S100B protein regulates astrocyte shape and migration via interaction with Src kinase: implications for astrocyte development, activation and tumor growth. J Biol Chem. (in press) 吳亮均-Chassin C., Hornef M.W., Bens M., Lotz M., Goujon J.M., Vimont S., Arlet G., Hertig A., Rondeau E., Vandewalle A. (2007). Hormonal control of the renal immune response and antibacterial host defense by arginine vasopressin. J. Exp. Med. 204(12):2837-52.
第6週	3/24	楊尚樺-White K.N., Ejim A.I., Walton R.C., Brown A.P., Jugdaohsingh R., Powell J.J., and McCrohan C.R. (2008).Avoidance of aluminum toxicity in freshwater snails involves intracellular silicon-aluminum biointeraction. Environ. Sci. Technol. 42(6):2189-2194. 徐健翔-Süel G.M., Kulkarni R.P., Dworkin J., Garcia-Ojalvo J., and Elowitz M.B. (2007). Tunability and noise dependence in differentiation dynamics. Science 315(5819):1716-1719.
第7週	3/31	蔡向榮-Burlison J.S., Long Q., Fujitani Y., Wright C.V., and Magnuson M.A. (2008). Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol. 316(1):74-86. 謝瑩蓉-Boland B., Kumar A., Lee S., Platt F.M., Wegiel J., Yu W.H., Nixon R.A. (2008). Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci. 28(27):6926-6937.
第8週	4/7	蔡宇臣-Zou J., Chang S.C., Marjanovic J., and Majerus P.W. (2009). MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis. J Biol Chem. 284(4):2064-2071. 盧映儒-Chan S.L., Ong T.C., Gao Y.F., Tiong Y.S., Wang de Y., Chew F.T., and Mok Y.K. (2008). Nuclear Magnetic Resonance Structure and IgE Epitopes of Blo t 5, a Major Dust Mite Allergen. J Immunol. 181(4):2586-2596.
第9週	4/14	Mid-term
第10週	4/21	李飛葦-Ebihara A., Farrar D.R., and Ito M. (2008). The sporophyte-less filmy fern of eastern North America Trichomanes intricatum (Hymenophyllaceae) has the chloroplast genome of an Asian species. Am. J. Bot. 95(12): 1645-1651. 邱顯壹 Nishida K.M., Saito K., Mori T., Kawamura Y., Nagami-Okada T., Inagaki S., Siomi H., and Siomi M.C.(2007). Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad. RNA (11):1911-1922.
第11週	4/28	盂曾賢-Choi S., Yang Y.M., and Chae, J. (2008). Surface plasmon resonance protein sensor using Vroman effect. Biosens. Bioelectron. 24(4): 893-899. 何建鴻-Napadow V., Kettner N., Liu J., Li M., Kwong K.K., Vangel M., Makris N., Audette J., and Hui K.K. (2007). Hypothalamus and amygdala response to acupuncture stimuli in Carpal Tunnel Syndrome. Pain 130(3):254-266.
第12週	5/5	陳依瑩-Romero M.L. and Wikelski M. (2006). Diurnal and nocturnal differences in hypothalamic-pituitary-adrenal axis function in Gal'apagos marine iguanas. Gen. Comp. Endocrinol. 145: 177-181. 薛穎超-Feichtner S., Inführ D., Achatz-Straussberger G., Schmid D., Karnowski A., Lamers M., Rhyner C., Crameri R., and Achatz G. (2008). Targeting the extracellular membrane-proximal domain of membrane-bound IgE by passive immunization blocks IgE synthesis in vivo. J Immunol. 180(8):5499-505.
第13週	5/12	葉潛之-Hillmer A.M. and Hanneken S. (2005). Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia. Am. J. Hum. Genet. 77(1):140-148. 薛孝亭-Iyer C., Kosters A., Sethi G., Kunnumakkara A.B., Aggarwal B.B., and Versalovic J. (2008). Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling. Cell Microbiol. 10(7):1442-1452.
第14週	5/19	陳鏡文-Homann D., Dummer W., Wolfe T., Rodrigo E., Theofilopoulos A.N., Oldstone M.B., and von Herrath M.G. (2006). Lack of intrinsic CTLA-4 expression has minimal effect on regulation of antiviral T-cell immunity. J Virol. 2006 Jan;80(1):270-280. 陳瀅淳-Hoffman C.L., Ruiz-Lambides A.V., Davila E., Maldonado E., Gerald M.S., and Maestripieri D. (2008). Sex differences in survival costs of reproduction in a promiscuous primate. Behav. Ecol. Sociobiol. 62:1711–1718.
第15週	5/26	謝舒丞-Leung K.W., Pon Y.L., Wong R.N., and Wong A.S. (2006). Ginsenoside-Rg1 Induces Vascular Endothelial Growth Factor Expression through the Glucocorticoid Receptor-related Phosphatidylinositol 3-Kinase/Akt and -Catenin/T-cell Factor-dependent Pathway in Human Endothelial Cells. J. Biol. Chem. 281(47):36280-36288. 吳庭光-Gregson M. A., Pratchett M. S., Berumen M. L., and Goodman B. A. (2008). Relationships between butterflyfish (Chaetodontidae) feeding rates and coral consumption on the Great Barrier Reef. Coral Reefs 27:583–591.
第16週	6/2	張珮瑩-Tan H.Y., Nicodemus K.K., Chen Q., Li Z., Brooke J.K., Honea R., Kolachana B.S., Straub R.E., Meyer-Lindenberg A., Sei Y., Mattay V.S., Callicott J.H., and Weinberger D.R. (2008). Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans. J Clin Invest. 118(6):2200-2208. 劉家宏-Orengo D.J., and Aguadé M. (2007). Genome scans of variation and adaptive change: extended analysis of a candidate locus close to the phantom gene region in Drosophila melanogaster. Mol. Biol. Evol. 24(5):1122-1129.
第19週	6/16	Final